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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f4e45a2fb4ad1dd6af31773c73a4428e77da0d19f66c40a1398da7bac940cfc' 
  AND token = 'QI77tPyLL9OrFk4j2jb01dR6c7oj5oXMhs3LqxDcKTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}