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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fb03d3032b2f1f349b79edfc635201d670c3e2fdf09abf8e61d7d4ee136e282' 
  AND token = '2Q2y8FxpSKDtGtwQC6p8+3NzXGEh4SXVwXAh4Hc9Bq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}