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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5311b378ca2d74617cba33a9f358ff14e7f089eca1d9851432f36174cbe8f44' 
  AND token = 't24DXaAvSaBzqn35o74a2WR1DD9fkpjlVz2ee23eehQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}