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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc82273b1b8534afe04b2962ec622d37ca34c02cf1cf3c8eea54553344d5da67' 
  AND token = '4gYw2s0TpQIwn5dhgCh4xOQy/ufFK9Td1O+ix+lDAZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}