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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9608ffc28f5f6f1f4bd0ee8f40521456ae8886384420c51712d8f61e1d332480' 
  AND token = 'v+31ZRbg/XOyllWrciIcdbT6TBmXiF7k18uQNBTfnu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}