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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c3224c1dd512aa76805bddddea6dfbfb66b631c432adb27f6eb97d4d4359da0' 
  AND token = 'oonmbu5QalHon+kxr8rPzbY2qpH2g2HQ8KaaRQ8YjVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}