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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b9b115f9a65e94e2b315fd9fd452c0299bf839ab9bbec377ceed68dc468df67' 
  AND token = 'DGVk4+kZXPko+2us+Q2msWff3m3YbZyckgl8vmwBbA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}