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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd362181fc2d5d837b6191ec388729a7833392c82d1c6d2747e03344c5ed8958d' 
  AND token = 'B4Uc/A7QKnvWI38WR26AQdTzQBDYNw/0iaGXh06zrNo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}