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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492a8bae28af0febf545f2c104b4ab730403f966d2dc172ad6a84c227de77aac' 
  AND token = 'hMhnXGStz8bw3rIkaFjCXqlaGKIWf3qwdebXI8zH2oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}