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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37a65010c65911bcf868c8ac2ae15246b6ef456d08be802d0e31c14ea46fe23' 
  AND token = 'xrBXI1M5fkZQxkJQdXoarjGRt6OHBp/9b2F41vz+Hwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}