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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6ca319be1f12b2a8e47ca6b80bfbdaf6468590f2767b1ee2659e68e7450581' 
  AND token = 'ALSekXjGQQCXTLmITOSwXJ9WnmBLItLNL0q3zxYRyzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}