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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8320e33e60516ee4287bb9776c74b60f8bbfd6ecb42c811ed02e93a19f2e655' 
  AND token = 'cYOWvjnJrn+7zMIJPy+0+Pnk3EBoODWnSG7f+6EaX80=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}