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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a9a4554cd7f24f537ed352e7345a5510e6d97a3dc19494c4d184179fad8fa83' 
  AND token = 'btgDF4+tW6xxYXEQJx1yErS5SlXallZriSNrbO2fHZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}