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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f599e63ff448853a2afcc1009db8369075d5fddcf692b8c1adb7a2e714c93dd' 
  AND token = 'RQhRy9veIDpdP7ZpWMLB657wKHVB8ifSkATUdQw689I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}