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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2b5d0f2c211f7e8f3089c26c8cc7160d7e45b2b9f65646ebde44410c71fce51' 
  AND token = 'X1GLYxrcMf6kJQtCwAkWX+M/hM9BR1wNjbZ5MmmlcP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}