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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d1c6660acf880bf4c6a7f086151239453e04737f21d14af7b7f8c2c82a4f7e6' 
  AND token = 'mk9DogOOWUBx3fAGCOyAvktxdPOF1Tqrp1Qsw+cON8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}