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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5618e75e73602e30dd02b6b5ccbd3837478aaa921ac487a8252c8a71fce3a573' 
  AND token = 'v2EHi+dMSucXCdYsZeNkAJTWKArEjbfZPX3Nr7bEUvk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}