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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33443ac202105baf4adc3f47cc8f322158e6bc57bfe350685a1b83af4483487c' 
  AND token = 'CyQYdz5X/AL5m9CBXYbleGeiK2OTbfqkfgEEAq69t+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}