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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8393e24007c4ddad682db29cbdfb6ba8678e7503d18a5156246cbeb6c19cf1d' 
  AND token = 'y6Cqikoz/WRZffbTwSL3+FYnK/WT3cCv8pu1oFoqdp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}