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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec66267765c07f9aeabfaeb5eb658324ffd4fda1b01a83af3174fbcff223cc8e' 
  AND token = 'MIAvq32HnL/uvZUGY9PfLTj1IYveclgAaucrIiUXRG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}