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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '579b61f765383a5e858dccfb69af39750cb762fb474aa1ed9e5589ecee63d77d' 
  AND token = 'aDKfrQLRTnmRFRJbySO8+rh8XxZJbYlYvSGHoUO0tiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}