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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2387ecda9dca57bcbc891a277d74bf6a772ab1ea98f9829a8a2b2d412d526b8f' 
  AND token = 'YM1V+2/9YlPG37jQXFFBeiNyk65N7w0dEIr5zozFdf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}