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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c16b5d6338d81f4d421e4edaea5102c709258dcfe2e758f2ae2cfe4fd4a37e1' 
  AND token = 'n4hX3s4n/f8d8g/gA8BtisacJkqwVpBQ5cYvZCMpSm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}