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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34558689a1b8da5caf70294d389c7609f8fe8bcbbadbdb9a32e91ef2197dc4dc' 
  AND token = 'Cr7y8wYf9I3Td4UfoAQjS2Qc/Q0fFOLRZFol/EozA14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}