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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10f7e18cb536bcf225218ab2c9770eeda2303913c39a68b5a8c66346050b5961' 
  AND token = '0fkDQuu+LmPSU8/rAPeg9YDUaygDxg01Pa0Ua0vD//Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}