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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1291a0a375852509e275b243f07d900af179d0efa502b967d049dba9975af05' 
  AND token = 'i52uDRDbPMc/FVu0W223k6b8WbalWXFkvDyc85+IQjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}