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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cc45f539c6b327ba0927e7b79c8e7300e891d359f6dca4fdfd18478df221349' 
  AND token = 'EW1LZFeZsm06fWhWjeBI7kIh8Y1gWg81jEv0y6aMncU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}