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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73090a99e19061f285ba588f0e23e8e9fc0a477315e0af3bcbf56b98d89f5296' 
  AND token = 'VF+/O32A9vNcaJZPsUUwwv5vjIHvFKTlwaTbAk4zri4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}