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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7481f95f42c194678c453fa8b4e344334fa38dc71474dbe41c9f41cc1d4847df' 
  AND token = 'nsjI1hjgsx3PTpdHfT98qg7Prz4yOo4TFKGEXExRLzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}