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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f98335d1c4fa96cf0036349c76a3f00f550967a93e5e3a54d647539338e90b8' 
  AND token = 'x1SwjcdeuzGRD+K2VXF6efxbJnuNrbnm8wDd+aXbIyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}