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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c4e778469edc008c490bbd4c11d84cbefd02297490f8b7fc4fb3458718ece56' 
  AND token = 'vr0X+60tnvnWz/793YzQvRQXy76V+0Y2GKcWlkNVSX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}