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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eab37f4e0f98a323d5abdd1d9c4e7fbf106ec23713ee6253d9a06e61f8e09740' 
  AND token = 'ZIAgTvAdtdoCgMBn2wBa9JIhz1Ht1dGKn98n24pxeZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}