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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d03f9ebbb49d0a838eec72f7eb80db5b9c06cd2183acf378e59e378ea71d1f1' 
  AND token = 'NSE8srHDl9taUMAjFMlEgbP3u4wzJGn+kKkWIrMg0zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}