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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a412e493210691b0b68b8dd577bab3ffcaa7c19ce5ddc573e6f43e756a518a2f' 
  AND token = 'nx4c685fgm4/VIQ4siGH1l4VcsUrCKY7Ks/c2nC8mcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}