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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e49e1ed805a8d8d72f914bf65975646a94b580c86b6dbe4447debaa43a90600' 
  AND token = 'kuRWtUEXGyM3vdRMZY3ylOflwZq9z9eieThK3/Nzeao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}