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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '869720c7be376ed8c59880cc55f5560178624623ee2dde38fe35c7ffd26165f1' 
  AND token = 'jmO+JKxd54Y0BQMwMJvXwfK9n2k0rFW4HoSG0RxJkD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}