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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b3f95a469b4bd8daa6e30d5e4e55f35925d0e6a81926e81d4967b36a1395457' 
  AND token = 'BefmI6xidYHisPQ6LI4k/LAG/UEsyCmm6LWYMqcZ8/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}