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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f44274315224add957466fd61ecda2236f319ff19bcd9ddd32c3ecc76d11ca3' 
  AND token = 'BFq5uYw3sRUyugHEP64vpOHgxClR/lWJdjA4E+xbMfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}