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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef5b45bc49c5283472cadcf16b920e2d12fbb1ab734e584a78a84d4345bcaff' 
  AND token = 'Nb9l4V6y3Zo+tmXJblXTC6Etx5folR0C8JQhx4SP+QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}