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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9359f2ab787a253842f881e93b2df233cf5875c892f59eb7089071a28b54f304' 
  AND token = 'ggip+l6Zcg8kkAc9duJg28Y6W/AR+Wg86AVNMdeS2gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}