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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ce678231b0f3c677ce072a6cff9dcc68c4f7ef1581bf9585d2060fb23fd4a71' 
  AND token = 'N5egn/97YTSNsqjng1WHSAkn7dJsqdTFSOHppFDn82Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}