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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af00d8ba305827fd866d433987a33b5d7e61510d5181e71a4af9d88032b4aa9c' 
  AND token = '59qJaZmcQiBmzejMrCRl0TlApr5OJGY629Gbpq+adKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}