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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c8e920a4660fcd57f5483287301f38d47dd46c3be1a847fd2acdd03dd75602' 
  AND token = '+gXWS4IZjgJKBuHMMpdHcRY+dVjS+sjpDEg6NKH+Pik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}