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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '466c7a5db1a40ea2ade8ff94ccd8d01978e4f4bd0cc04e32be51e7d3cce57a10' 
  AND token = 'ewwRC+O4F38f2xSqrRKaPXuDtRH1WHwDH+pVo8bFcfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}