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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3165005646c15251c19a00fecf9fd445e838e6a35907589e746497850e5db8cd' 
  AND token = 'PiHB/laZzpIYsZAhccLa1p+6wKdKt3mM+ndolFn97oc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}