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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88b4d6ee8ce2a367f3f6bfb4e6ba73f537e7028a76765968ed0e643b42d01864' 
  AND token = 'gIk61iYaewQ8vv2gUCrqNZHxf9dz3lbi1JOyAZWDCgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}