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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48832cde1af61877b838e01aa08c7e80c03b00744b842bf327328b815609fba2' 
  AND token = 'GuG/i5Go/RDh83a9v2E6F18+v6XywhM2hI9sa/MPUaY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}