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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27676c2723267b76988562c0d87e4be0c7587ef7ffbf27c6c4eecb16f33c37f0' 
  AND token = 'LKb++LTEysafMpM0VY/jD2bSg0LO+4SUmJmCG2WtmLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}