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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df446bdf9112709d72dbd56dc53dabb362f969c88e3d86cc1f3d50083c99f4e2' 
  AND token = 'tw7i3ZWOZzcvMfCd/rcW6WwcgwGs9olcYrKmL223if0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}