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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e6153ed4246f068aa0264e4a0296596bcf900ba1ce4a2d8129fae12a11f6ca9' 
  AND token = 'WOG2z4cNEpQdo/thuCS7h/DogYQgFyKqSla2VwFYT5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}